A Korean lab found cancer’s DNA-repair off-switch. In a mouse.
A tool compound strips the DNA-repair proteins tumors use to dodge PARP inhibitors. Preclinical only — but the gap between treated and control animals is the story.
A tool compound strips the DNA-repair proteins tumors use to dodge PARP inhibitors. Preclinical only — but the gap between treated and control animals is the story.
The saltshaker gets the blame. Processed food does the work — roughly 71% of daily sodium intake versus 6–20% from what you add at the table.
A 27-year wait for a UV filter Europeans have used for decades. The approval is routine; the timeline is not.
The week’s most important findings, with the sourcing intact. One email, every Sunday.
Antibodies that bind fentanyl before it reaches the brain. The DoD funded it; the overdose epidemic gave it urgency; Phase 1 trials will tell us whether the immune system can do what naloxone does.
If amyloid is the body’s response to something else, clearing it may not be clearing the disease. This drug bets differently.
Omega-3s shifted regulatory T-cell ratios in an animal model of Type 1 diabetes. Promising mechanism, long road to a human trial.
The trial failed on progression-free survival. The company’s communications found a subgroup. Read the prespecified endpoint first.
A government-mandated planogram shift covering thousands of stores traces back to a single small study. The evidence base deserves a closer read.
Not a fringe hearing. A formal subcommittee proceeding with named witnesses and entered documents. What went into the record, and what it means.
Same reagents, same analyzer, same 23 values. Twelve-fold price spread across facilities in a single metro area. The billing codes are identical.
Controlled vortex combustion accelerates burn efficiency enough to meaningfully cut particulate output. The physics are counterintuitive; the numbers are real.