The First Cohort homepage — evidence-led medical research news in a classic broadsheet layout with lead story, secondary rail, latest stories river, and investigations strip

The First Cohort
Medical research, with the receipts
Cancer
A Korean lab found cancer's DNA-repair off-switch. In a mouse.
A tool compound strips the DNA-repair proteins tumors use to dodge PARP inhibitors. Preclinical only — but the gap between treated and control animals is the story.
Tumor clearance at 8 weeks
94% Treated Control 12%
Source: Kim et al., preclinical mouse model, 2026
Also today
Metabolic
Where your sodium actually comes from
Drugs & FDA
Europe had this sunscreen in 1999. The FDA approved it Tuesday.
Infectious Disease
A DoD-funded fentanyl vaccine is headed to Phase 1
Brain & Aging
The Alzheimer's drug that bets the plaques are a symptom
Newsletter
The Sunday Cohort
One weekly dispatch. The stories that held up.
Latest
Autoimmune
Fish oil rewired the T-cells in non-obese diabetic rats
Cancer
ALTAIR missed its endpoint. The press tour found something else.
Nutrition
The thin trial behind England's next supermarket-layout mandate
Investigations
A Senate subcommittee just put the COVID-shot cancer question on the record
The $401 CBC and the $32 CBC are the same test
A 16-foot fire tornado burned an oil slick with 40% less soot